- Spring 2024
- Location: Animal Science A128
- Time: 9:00-9:50am (MWF)
- Prerequisites: STAT-801A or equivalent, or permission of the instructor(s).
Texts and Reading Materials
Required textbook
- Falconer & Mackay, Introduction to Quantitative Genetics
Free Online Materials
- Graham Coop, Population Genetics notes
- Basic R: Quick online reference for data input, basic statistics, and plots.
- STHDA: Statistical tools for high-throughput data analysis.
Schedule Spring 2024
The HTML slides will likely be posted on Sunday pm for the next week. The slides are subject to change before the class.
Week 1: Allele and Genotype Frequencies (Ch1)
- 01-22 (M): Introduction [HTML]
- 01-24 (W): Hardy-Weinberg Equilibrium [HTML]
- 01-26 (F): Linkage Disequilibrium [HTML]
Week 2: Changes of Allele Frequency (Ch2 & Ch3)
- 01-29 (M): Migration, Mutation, and Selection [HTML]
- HW1 assignment in Canvas on Monday (Due Friday morning)
- 01-31 (W): Effectiveness of Selection [HTML]
- 02-02 (F): Genetic Drift [HTML]
- HW1 Due today at 9AM!
Week 3: Small Populations — Simplified Conditions (Ch3 & Ch4)
- 02-05 (M): Inbreeding [HTML]
- 02-07 (W): Effective Population Size [HTML]
- 02-09 (F): Heterozygosity [HTML]
Week 4: Population Structure and Neutrality test (Notes in Canvas)
Week 5: Neutrality Test (Notes in Canvas)
- 02-19 (M): Neutral theory [HTML]
- HW2 assigned in Canvas!
- 02-21 (W): Detecting natural selection [HTML]
- 02-23 (F): Journal article review [HTML]
- HW2 Due today!
- Journal article assigned for peer review (due in two weeks)
Week 6: Pedigreed Population and Close Inbreeding (Ch5)
- 02-26 (M): Pedigreed population [HTML]
- 02-28 (W): Coancestry [HTML]
- 03-01 (F): Relationship matrix [HTML]
- Watch recorded video in Canvas
Week 7: Statistical Foundations for Continuous Variation (Ch6 and Notes in Canvas)
- 03-04 (M): Statistical foundations of quantitative genetics [HTML]
- 03-06 (W): Continuous Variation [HTML]
- 03-08 (F): Journal Review Discussion [HTML]
- Peer review due
Week 8: No class
- Enjoy Spring Break!
Week 9: Population values and means (Ch7)
- 03/18 (M): Average effect of an allele [HTML]
- 03/20 (W): Breeding value, dominance, and interaction [HTML]
- 03/22 (F): Exam II (take home)